COVID vaccine update: Novavax’s is 90% effective

poster novavax US approval

American biotechnology firm Novavax said at this time that the COVID-19 vaccine it’s growing has proven to have 90.4% effectiveness in a Part 3 scientific trial carried out in the USA and Mexico.

The outcomes of the trial, which included 29,960 contributors, yielded an efficacy on par with that of vaccines from Pfizer-BioNTech and Moderna. It was additionally proven to defend towards newer, mutating strains of the coronavirus, together with the alpha variant now most prevalent within the nation.

Novavax’s vaccine candidate, nevertheless, has a mechanism that differs from Pfizer-BioNTech’s and Moderna’s, which each used novel methods that inject genetic materials to instruct the immune system to start producing illness antibodies. The Novavax candidate as a substitute provides a small quantity of the illness protein—like in conventional vaccines—to immediate the physique to combat it off and construct up immunity. However not like vaccines of the previous, it includes a lab-engineered protein grown in an insect cell.


With three vaccines already in use within the U.S., some specialists suppose the nation’s demand already has plateaued, and the U.S. Meals and Drug Administration might deny the Novavax candidate emergency use authorization in favor of recommending that it bear the extra rigorous customary means of full approval.

Nonetheless, it might show most useful in different less-resourced nations throughout the globe, which have lagged far behind the U.S. and the UK in vaccinating their populations. In India and Brazil, two nations affected by the worst COVID-19 outbreaks, solely 6% and 11% are inoculated, respectively. Within the U.S., the quantity stands at 44%.

Logistically, the Novavax candidate is additionally simpler to move than some main vaccines, as it may be saved at regular refrigeration temperatures versus the ultra-cold freezers Pfizer-BioNTech’s and Moderna’s require.

Based on Novavax CEO Stanley Erck, it’s almost definitely to roll out first in low- and middle-income nations by way of the worldwide COVAX initiative, which goals to attain equitable vaccine distribution worldwide. The corporate has pledged a complete of 1.1 billion doses to growing nations by way of this system.

Novavax, which was awarded $1.6 billion by the Trump administration’s Operation Warp Velocity program final yr, has but to carry a vaccine to market since its founding in 1987.